Tissue expression
Cell line expression
Protein structure
SMG6
SMG6 nonsense mediated mRNA decay factorC17orf31, EST1A, KIAA0732, SMG-6
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014]
Top validated antibodies |
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Biorbyt | orb221405 | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | PA5-60165 | 1 references | Polyclonal |
ICC
IHC |
|
LSBio | LS-B15630 | Polyclonal |
WB
IHC |
||
Cusabio Biotech Co., Ltd | CSB-PA773032LA01HU | Polyclonal |
EL
ICC
IHC
|
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Atlas Antibodies | HPA042932 | Polyclonal |
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider