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Protein structure
PLCZ1
Phospholipase C zeta 1NYD-SP27, PLCzeta
The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Top validated antibodies |
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| LSBio |  LS-B8469 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN2492800 |
Polyclonal |
WB
EL
IHC
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| OriGene | AP55157SU-N |
Polyclonal |
WB
EL
ICC
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| Biorbyt | orb78246 |
Polyclonal |
WB
EL
IHC
|
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| Cusabio Biotech Co., Ltd | CSB-PA768240LA01HU |
Polyclonal |
WB
EL
|
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