Tissue expression
Cell line expression
ITPR1
gene productACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
Featured antibodies
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0 references | Polyclonal |
WB
IHC |