SERTAD3

The protein encoded by this gene was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to normal cell lines. This protein has also been shown to be a strong transcriptional co-activator. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Description

SERTA domain containing 3

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

19 (40440844 - 40444335)

Ensembl ID

ENSG00000167565  (ver. 103.38)

Orthologs

Mouse Sertad3: ENSMUSG00000055200

UniProt

Q9UJW9

neXtProt

NX_Q9UJW9

Human splice variants
Mouse splice variants

Protein structure