PALM2AKAP2

This gene belongs to the paralemmin downstream gene (PDG) family defined in PMID:22855693. Paralemmin downstream genes may have evolved contiguously with the paralemmin genes and are associated with other paralemmin paralogs in humans and several other taxa. The gene encodes three distinct protein isoforms, the PALM2 isoform, the AKAP2 isoform and the PALM2-AKAP2 isoform. The biological significance of the PALM2-AKAP2 isoforms is yet unknown. Earlier, PALM2 and AKAP2 were annotated as separate genes and PALM2-AKAP2 was annotated as a readthrough gene. [provided by RefSeq, May 2019]

Description

PALM2 and AKAP2 fusion

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear bodies, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

9 (109498325 - 110172512)

Ensembl ID

ENSG00000157654  (ver. 103.38)

Orthologs

-

UniProt

Q9Y2D5, Q8IXS6

neXtProt

NX_Q9Y2D5, NX_Q8IXS6

Human splice variants

Protein structure