POLR2M

This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781. [provided by RefSeq, Oct 2013]

Description

RNA polymerase II subunit M

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

15 (57706695 - 57782762)

Ensembl ID

ENSG00000255529  (ver. 103.38)

Orthologs

Mouse Polr2m: ENSMUSG00000032199

UniProt

P0CAP2, Q6EEV4

neXtProt

NX_P0CAP2, NX_Q6EEV4

Human splice variants
Mouse splice variants

Protein structure