RGPD6

RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined. [provided by RefSeq, Jul 2008]

Description

RANBP2 like and GRIP domain containing 6

Tissue specificity

Low tissue specificity

Subcell location

Nuclear membrane, Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

2 (110513802 - 110577222)

Ensembl ID

ENSG00000183054  (ver. 103.38)

Orthologs

-

UniProt

Q99666

neXtProt

NX_Q99666

Human splice variants

Protein structure