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Protein structure
OCLN
OccludinPPP1R115
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Top validated antibodies |
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| Invitrogen Antibodies |  71-1500 |
457 references | Polyclonal |
WB
EL
ICC
IP
IHC
OA
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| antibodies-online | ABIN395206 |
5 references | Monoclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | H00004950-M01 |
2 references | Monoclonal |
WB
EL
ICC
IP
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| GeneTex | GTX85016 |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| NSJ Bioreagents | RQ5746 |
Polyclonal |
WB
EL
ICC
IHC
FC
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