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PLCD3
Phospholipase C delta 3This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  16792-1-AP |
2 references | Polyclonal |
WB
EL
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| antibodies-online | ABIN4346117 |
Polyclonal |
WB
ICC
IHC
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| Everest Biotech | EB11174 |
Polyclonal |
WB
EL
IHC
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| GeneTex | GTX123172 |
Polyclonal |
WB
IHC
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| Atlas Antibodies | HPA053665 |
Polyclonal |
WB
IHC
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