BS9217

antibody from Bioworld Technology, Inc

Targeting: VASH1 KIAA1036

Western blot (Data presented on provider website)

Antibody Data

Product number

BS9217

Provider

Bioworld Technology, Inc

Product name

Vasohibin (R302) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 268-324 of Human Vasohibin.

Description

Angiogenesis is mainly regulated by the balance of several different pro-angiogenic stimulators, such as vascular endothelial growth factor (VEGF) and a diverse group of endogenous inhibitors that are extrinsic to endothelial cells. Vasohibin is a secreted protein that is induced by a specific, self-regulating, feedback inhibition response to inhibit angiogenesis in an autocrine manner. It inhibits proliferation, migration, and network formation by endothelial cells. This function is specific for endothelial cells as it does not affect migration in other cell types. Vasohibin is primarily expressed in endothelial of the brain and placental tissues with highest abundance in fetal organs. VEGF and fibroblast growth factor 2 upregulate the expression of Vasohobin. In vitro, Vasohibin does not affect cancer cell proliferation, but does inhibit tumor growth and angiogenesis.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.