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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunohistochemistry [1]
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- Product number
- MA1-5784 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- HEF1 Monoclonal Antibody (2G9)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- This antibody detects HEF1 in human, mouse, and rat samples. This antibody does not recognize p130cas. It has not been tested on Sin1. This antibody mostly detects HEF1 localized at the focal adhesion sites.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2G9
- Vial size
- 50 µL
- Concentration
- 1 mg/mL
- Storage
- Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Submitted references p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade.
A novel inhibitor of focal adhesion signaling induces caspase-independent cell death in diffuse large B-cell lymphoma.
Zeinieh M, Salehi A, Rajkumar V, Barker PA
Journal of cell science 2015 Feb 1;128(3):447-59
Journal of cell science 2015 Feb 1;128(3):447-59
A novel inhibitor of focal adhesion signaling induces caspase-independent cell death in diffuse large B-cell lymphoma.
Bosch R, Dieguez-Gonzalez R, Céspedes MV, Parreño M, Pavón MÁ, Grañena A, Sierra J, Mangues R, Casanova I
Blood 2011 Oct 20;118(16):4411-20
Blood 2011 Oct 20;118(16):4411-20
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Immunohistochemistry analysis of HEF1 in PFA-fixed paraffin embedded normal breast tissue and ductal carcinoma using HEF1 monoclonal antibody (Product # MA1-5785).
