HPA003360

antibody from Atlas Antibodies

Targeting: OPTN FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA003360

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA003360, RRID:AB_1079528

Product name

Anti-OPTN

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human OPTN, Gene description: optineurin, Alternative Gene Names: FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP, Validated applications: WB, IHC, ICC, Uniprot ID: Q96CV9, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion

O'Loughlin T, Kruppa A, Ribeiro A, Edgar J, Ghannam A, Smith A, Buss F
Journal of Cell Science 2020;133(12)

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Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria

Kruppa A, Kishi-Itakura C, Masters T, Rorbach J, Grice G, Kendrick-Jones J, Nathan J, Minczuk M, Buss F
Developmental Cell 2018;44(4):484-499.e6

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Disruption of macrophage pro‐inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients

Smith A, Sewell G, Levine A, Chew T, Dunne J, O'Shea N, Smith P, Harrison P, Macdonald C, Bloom S, Segal A
Immunology 2014;144(1):45-55