FNab02486

antibody from FineTest Biotech

Targeting: DNMT3L MGC1090

Western blot

ELISA

Antibody data

Submit

Validation data

Product number: FNab02486 - Provider product page
Provider: FineTest Biotech
Product name: DNMT3L antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4(H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: DNA(cytosine-5-)-methyltransferase 3-like
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

DNMT3L protein structure - FNab02486 shown in red.