NB100-1619

antibody from Novus Biologicals

Targeting: PNOC N/OFQ, NOP, PPNOC

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

NB100-1619

Provider

Novus Biologicals

Proper citation

Novus Cat#NB100-1619, RRID:AB_10002592

Product name

Rabbit Polyclonal Nociceptin Antibody

Antibody type

Polyclonal

Description

Unpurified. Nociceptin

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.05 ml

Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

References

Submitted references

Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats.

Kallupi M, Carrette LLG, Kononoff J, Solberg Woods LC, Palmer AA, Schweitzer P, George O, de Guglielmo G
Proceedings of the National Academy of Sciences of the United States of America 2020 Jan 28;117(4):2140-2148

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Changes in nociceptin/orphanin FQ levels in rat brain regions after acute and chronic cannabinoid treatment in conjunction with the development of antinociceptive tolerance.

Ulugol A, Topuz RD, Gunduz O, Kizilay G, Karadag HC
Fundamental & clinical pharmacology 2016 Dec;30(6):537-548

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry: Nociceptin Antibody [NB100-1619] - This orphanin FQ robustly stains nerve fibers in brain and spinal cord. Animals were treated with colchicines to visualize orphanin FQ-expressing cell bodies. Staining was blocked by preabsorption with the cognate peptide.