BS3005

DPYSL2 antibody from Bioworld Technology, Inc
CRMP2, DHPRP2, DRP-2, DRP2

Antibody data

Product number
BS3005
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3005, RRID:AB_1663567
Product name
DRP 2 (P510) polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS3005
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 468-532 of Human DRP-2.
Description
Dystrophin, utrophin and dystrophin-related protein 2 (DRP2) are Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin is expressed in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. Evidence suggests that the upregulation of utrophin (also known as DRP1) can reduce the dystrophic pathology. DRP2 is principally expressed in the brain and spinal cord. Analysis of DRP2 expression in rat brain on SDS-PAGE reveals a characteristic quartet of bands from 100-120 kDa. DRP2 exhibits a punctate staining pattern of rat neuronal dendrites and in neuropil. DRP2 forms a complex with dystroglycan at the surface of myelin-forming Schwann cells and may play a role in the terminal stages of myelinogenesis in the peripheral nervous system. The gene encoding human DRP2 maps to chromosome Xq22.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -