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Learn10022-1-AP
antibody from Proteintech Group
Targeting: BIRC2
API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 10022-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10022-1-AP, RRID:AB_2063790
- Product name
- cIAP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated cIAP1 antibody (Cat. #10022-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRAF3 in T Cells Restrains Negative Regulators of LAT to Promote TCR/CD28 Signaling.
Chlorogenic acid inhibits the proliferation of human lung cancer A549 cell lines by targeting annexin A2 in vitro and in vivo.
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- κ B and NF- κ B-mediated cellular FLICE-inhibitory protein.
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.
Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.
The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.
Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling.
Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells.
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis.
Arkee T, Hostager BS, Houtman JCD, Bishop GA
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):322-332
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):322-332
Chlorogenic acid inhibits the proliferation of human lung cancer A549 cell lines by targeting annexin A2 in vitro and in vivo.
Wang L, Du H, Chen P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110673
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110673
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- κ B and NF- κ B-mediated cellular FLICE-inhibitory protein.
Yuan Z, Yuan Z, Hasnat M, Zhang H, Liang P, Sun L, Jiang Z, Zhang L
Acta pharmaceutica Sinica. B 2020 May;10(5):861-877
Acta pharmaceutica Sinica. B 2020 May;10(5):861-877
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.
Zachari M, Gudmundsson SR, Li Z, Manifava M, Cugliandolo F, Shah R, Smith M, Stronge J, Karanasios E, Piunti C, Kishi-Itakura C, Vihinen H, Jokitalo E, Guan JL, Buss F, Smith AM, Walker SA, Eskelinen EL, Ktistakis NT
Developmental cell 2019 Sep 9;50(5):627-643.e5
Developmental cell 2019 Sep 9;50(5):627-643.e5
Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.
Chen SM, Lin TK, Tseng YY, Tu CH, Lui TN, Huang SF, Hsieh LL, Li YY
Cancer medicine 2018 Aug;7(8):3988-4003
Cancer medicine 2018 Aug;7(8):3988-4003
The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis.
Liu TH, Zheng F, Cai MY, Guo L, Lin HX, Chen JW, Liao YJ, Kung HF, Zeng YX, Xie D
Oncotarget 2016 May 3;7(18):25836-48
Oncotarget 2016 May 3;7(18):25836-48
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.
Wu P, Zhu X, Jin W, Hao S, Liu Q, Zhang L
Biochemical and biophysical research communications 2015 May 1;460(2):183-90
Biochemical and biophysical research communications 2015 May 1;460(2):183-90
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz M, Stilmann M, Arslan SÇ, Khanna KK, Dittmar G, Scheidereit C
Molecular cell 2010 Oct 8;40(1):63-74
Molecular cell 2010 Oct 8;40(1):63-74
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.
Hostager BS, Fox DK, Whitten D, Wilkerson CG, Eipper BA, Francone VP, Rothman PB, Colgan JD
PloS one 2010 Jun 30;5(6):e11380
PloS one 2010 Jun 30;5(6):e11380
Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling.
Peters AL, Bishop GA
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):6555-62
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):6555-62
Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells.
Akao Y, Nakagawa Y, Iio A, Naoe T
Leukemia research 2009 Nov;33(11):1530-8
Leukemia research 2009 Nov;33(11):1530-8
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
Varfolomeev E, Goncharov T, Fedorova AV, Dynek JN, Zobel K, Deshayes K, Fairbrother WJ, Vucic D
The Journal of biological chemistry 2008 Sep 5;283(36):24295-9
The Journal of biological chemistry 2008 Sep 5;283(36):24295-9
Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis.
Santoro MM, Samuel T, Mitchell T, Reed JC, Stainier DY
Nature genetics 2007 Nov;39(11):1397-402
Nature genetics 2007 Nov;39(11):1397-402
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 10022-1-AP(cIAP1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using BIRC2 antibody 10022-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10022-1-AP(cIAP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 10022-1-AP(cIAP1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
