BS60294
antibody from Bioworld Technology, Inc
Targeting: IFNA1
IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60294 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- IFN Ï« polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human IFN-Ï«.
- Description
- The genes encoding type I interferons(IFNs),which include 14 IFN-Ï« genes (two of which are IFN-Ï«1 and IFN-Ï«13), one IFN-ÉÇ gene, one IFN-Àß (also known asIFN-Ï«II1) gene and a number of IFN-Àßpseudogenes, are clustered on human chromosome 9. IFN-Ï«and -ÉÇ are cytokinesthat arewidelyknown to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities, and are increasingly used clinicallyto treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-Àß is antigenically different from human IFN-Ï«, IFN-ÉÇorIFN-ÎÛ, butis a component of naturalmixtures ofIFNspecies produced byvirus-induced leukocytes or Burkitt£ªslymphoma cells. The type I interferon receptor (IFN-Ï«R) interactswith IFN-Ï«, IFN-ÉÇ and IFN-Àß, and seemsto be a multi-subunit receptor.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of IFN-¦Á pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:NIH-3T3 whole cell lysateLane3:H9C2 whole cell lysate