Antibody data

Product number
BS4660 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Casein Kinase IIÉÇ (phospho S209) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Casein Kinase IIÉÇ around the phosphorylation site of Serine 209.
Description
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIÏ«, ÎÛ, š÷ and Ñ´, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an Ï«2ÉÇ2 or an Ï«Ï«'ÉÇ2 structure. The Ï« catalytic subunit is stimulated by the ÉÇ regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CSNK2B protein structure - BS4660 shown in red.