11-3041

antibody from ABEOMICS Inc.
Targeting: TLR1 CD281, KIAA0012, rsc786
Provider product page for 11-3041

Antibody data

Product number
11-3041 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-TLR1 Antibody
Antibody type
Polyclonal
Description
Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis, and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
Reactivity
Human, Mouse
Host
Rabbit
Antigen sequence
A partial length recombinant TLR1 p
rotein (amino acids 300-500) was us
ed as the immunogen for this antibo
dy.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
TLR1 protein structure - 11-3041 shown in red.