334502

antibody from BioLegend

Targeting: TLR1 CD281, KIAA0012, rsc786

Immunocytochemistry

Immunoprecipitation

Antibody data

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Validation data

Product number: 334502 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#334502, RRID:AB_1186023
Product name: Purified anti-human CD281 (TLR1)
Antibody type: Monoclonal
Antigen: Human TLR1 transfected Ba/F3
Description: Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been indentified. Toll-like receptor 1 (TLR1), known as CD281, is expressed on monocytes/macrophages, dendritic cells, and granulocytes and some lymphocytes at low levels. By association with TLR2, TLR1 is a coreceptor involved in the response to diverse set of pathogens, such as triacylated lipopeptidess (but not diacylated lipopeptides), peptidoglycans, lipoteichoic acid.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

TLR1 protein structure - 334502 shown in red.