ABIN310565

antibody from antibodies-online

Targeting: SLC19A1 FOLT, RFC1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN310565

Provider

antibodies-online

Product name

anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-SLC19A1 antibody: synthetic peptide directed towards the N terminal of human SLC19A1

Reactivity

Human

Host

Rabbit

Antigen sequence

MVPSSPAVEKQVPVEPGPDPELRSWRHLVCYLCFY
GFMAQ IRPGESFITP


Vial size

0.1 mg

References

Submitted references

The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier.

Halwachs S, Lakoma C, Schäfer I, Seibel P, Honscha W
Molecular pharmacology 2011 Oct;80(4):621-9

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Pralatrexate is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies.

Marchi E, Paoluzzi L, Scotto L, Seshan VE, Zain JM, Zinzani PL, O'Connor OA
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Jul 15;16(14):3648-58

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Transcriptional regulation of the human reduced folate carrier A1/A2 promoter: Identification of critical roles for the USF and GATA families of transcription factors.

Payton SG, Liu M, Ge Y, Matherly LH
Biochimica et biophysica acta 2005 Nov 10;1731(2):115-24