Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14008-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14008-1-AP, RRID:AB_2096356
- Product name
- ELAVL2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ELAVL2 antibody (Cat. #14008-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mature mRNA processing that deletes 3' end sequences directs translational activation and embryonic development.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages.
The SYNGAP1 3'UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK.
Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons.
Dihydroartemisinin Attenuates Hypoxia-Induced Pulmonary Hypertension Through the ELAVL2/miR-503/PI3K/AKT Axis.
HuB and HuD repress telomerase activity by dissociating HuR from TERC.
Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma.
ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
New clinicopathological associations and histoprognostic markers in ILAE types of hippocampal sclerosis.
Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.
ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism.
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.
Takada Y, Fierro L, Sato K, Sanada T, Ishii A, Yamamoto T, Kotani T
Science advances 2023 Nov 24;9(47):eadg6532
Science advances 2023 Nov 24;9(47):eadg6532
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.
Hsu YH, Pintacuda G, Liu R, Nacu E, Kim A, Tsafou K, Petrossian N, Crotty W, Suh JM, Riseman J, Martin JM, Biagini JC, Mena D, Ching JKT, Malolepsza E, Li T, Singh T, Ge T, Egri SB, Tanenbaum B, Stanclift CR, Apffel AM, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Carr SA, Schenone M, Jaffe J, Fornelos N, Huang H, Eggan KC, Lage K
iScience 2023 May 19;26(5):106701
iScience 2023 May 19;26(5):106701
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
Pintacuda G, Hsu YH, Tsafou K, Li KW, Martín JM, Riseman J, Biagini JC, Ching JKT, Mena D, Gonzalez-Lozano MA, Egri SB, Jaffe J, Smit AB, Fornelos N, Eggan KC, Lage K
Cell genomics 2023 Mar 8;3(3):100250
Cell genomics 2023 Mar 8;3(3):100250
RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages.
Susanto TT, Hung V, Levine AG, Kerr CH, Yoo Y, Chen Y, Oses-Prieto JA, Fromm L, Fujii K, Wernig M, Burlingame AL, Ruggero D, Barna M
bioRxiv : the preprint server for biology 2023 Dec 7;
bioRxiv : the preprint server for biology 2023 Dec 7;
The SYNGAP1 3'UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK.
Yokoi S, Ito T, Sahashi K, Nakatochi M, Nakamura R, Tohnai G, Fujioka Y, Ishigaki S, Udagawa T, Izumi Y, Morita M, Kano O, Oda M, Sone T, Okano H, Atsuta N, Katsuno M, Okada Y, Sobue G
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Nov 23;42(47):8881-8896
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Nov 23;42(47):8881-8896
Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons.
De Gregorio R, Subah G, Chan JC, Speranza L, Zhang X, Ramakrishnan A, Shen L, Maze I, Stanton PK, Sze JY
Development (Cambridge, England) 2022 Nov 1;149(21)
Development (Cambridge, England) 2022 Nov 1;149(21)
Dihydroartemisinin Attenuates Hypoxia-Induced Pulmonary Hypertension Through the ELAVL2/miR-503/PI3K/AKT Axis.
Cai H, Fan S, Cai L, Zhu L, Zhao Z, Li Y, Yao Y, Huang X, Wang L
Journal of cardiovascular pharmacology 2022 Jul 1;80(1):95-109
Journal of cardiovascular pharmacology 2022 Jul 1;80(1):95-109
HuB and HuD repress telomerase activity by dissociating HuR from TERC.
Cheng X, Gu X, Xia T, Ma Z, Yang Z, Feng HL, Zhao Y, Ma W, Ju Z, Gorospe M, Yi X, Tang H, Wang W
Nucleic acids research 2021 Mar 18;49(5):2848-2858
Nucleic acids research 2021 Mar 18;49(5):2848-2858
Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma.
Zhao WS, Yan WP, Chen DB, Dai L, Yang YB, Kang XZ, Fu H, Chen P, Deng KJ, Wang XY, Xie XW, Chen HS, Chen KN
American journal of cancer research 2019;9(6):1183-1200
American journal of cancer research 2019;9(6):1183-1200
ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
Kato Y, Iwamori T, Ninomiya Y, Kohda T, Miyashita J, Sato M, Saga Y
EMBO reports 2019 Dec 5;20(12):e48251
EMBO reports 2019 Dec 5;20(12):e48251
New clinicopathological associations and histoprognostic markers in ILAE types of hippocampal sclerosis.
Calderon-Garcidueñas AL, Mathon B, Lévy P, Bertrand A, Mokhtari K, Samson V, Thuriès V, Lambrecq V, Nguyen VM, Dupont S, Adam C, Baulac M, Clémenceau S, Duyckaerts C, Navarro V, Bielle F
Brain pathology (Zurich, Switzerland) 2018 Sep;28(5):644-655
Brain pathology (Zurich, Switzerland) 2018 Sep;28(5):644-655
Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
Bielle F, Ducray F, Mokhtari K, Dehais C, Adle-Biassette H, Carpentier C, Chanut A, Polivka M, Poggioli S, Rosenberg S, Giry M, Marie Y, Duyckaerts C, Sanson M, Figarella-Branger D, Idbaih A, Pola Network
Brain pathology (Zurich, Switzerland) 2017 Sep;27(5):567-579
Brain pathology (Zurich, Switzerland) 2017 Sep;27(5):567-579
ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.
Rotem N, Magen I, Ionescu A, Gershoni-Emek N, Altman T, Costa CJ, Gradus T, Pasmanik-Chor M, Willis DE, Ben-Dov IZ, Hornstein E, Perlson E
Scientific reports 2017 Mar 16;7:44500
Scientific reports 2017 Mar 16;7:44500
ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism.
Berto S, Usui N, Konopka G, Fogel BL
Human molecular genetics 2016 Jun 15;25(12):2451-2464
Human molecular genetics 2016 Jun 15;25(12):2451-2464
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.
Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R
Cell reports 2015 Aug 4;12(5):760-73
Cell reports 2015 Aug 4;12(5):760-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 14008-1-AP(ELAVL2 antibody) at dilution of 1:3000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 14008-1-AP(ELAVL2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ELAVL2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ELAVL2. This antibody recognizes human, mouse, rat, zebrafish antigen. The ELAVL2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.