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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4129 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4129, RRID:AB_1574512
- Product name
- DUSP4 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of DUSP4.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically.
Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7).
The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation.
Chen P, Hutter D, Yang X, Gorospe M, Davis RJ, Liu Y
The Journal of biological chemistry 2001 Aug 3;276(31):29440-9
The Journal of biological chemistry 2001 Aug 3;276(31):29440-9
Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7).
Smith A, Price C, Cullen M, Muda M, King A, Ozanne B, Arkinstall S, Ashworth A
Genomics 1997 Jun 15;42(3):524-7
Genomics 1997 Jun 15;42(3):524-7
The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation.
Chu Y, Solski PA, Khosravi-Far R, Der CJ, Kelly K
The Journal of biological chemistry 1996 Mar 15;271(11):6497-501
The Journal of biological chemistry 1996 Mar 15;271(11):6497-501
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of DUSP4 polyclonal antibody (Cat # PAB4129) in mouse brain tissue lysate (35 ug/lane). DUSP4 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with DUSP4 polyclonal antibody (Cat # PAB4129) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
