BS6708

antibody from Bioworld Technology, Inc
Targeting: PRL
Provider product page for BS6708
Western blot
Immunohistochemistry

Antibody data

Product number
BS6708 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PRL polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PRL.
Description
The anterior pituitary secretes a variety of hormones that are involved in cell growth, differentiation and development. Prolactin, a 226 amino acid protein, plays a role in multiple processes, including cell growth, reproduction and immune function. Full-length Prolactin, as well as an alternative splice product lacking the third exon, are secreted by endothelial cells involved in angiogenesis. In addition to its role in mammary developmant and lactation, Prolactin is known to play a role in the development of mammary cancer, acting as both a mitogen and a differentiating agent. Prolactin has also been shown to enhance the proliferation of B cell hybridomas, leading to an overall increase in antibody production. In addition, Prolactin has been demonstrated to reverse the antiproliferative effects of the immunosuppressive cytokine TGF-beta. Prolactin is also associated with a variety of autoimmune diseases, including arthritis and type 1 diabetes.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRL protein structure - BS6708 shown in red.