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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- TA307586 - Provider product page
- Provider
- OriGene
- Product name
- Rabbit monoclonal antibody against Dnmt1(clone EPR3521(2))
- Antibody type
- Monoclonal
- Description
- Rabbit monoclonal antibody against Dnmt1(clone EPR3521(2))
- Host
- Rabbit
- Conjugate
- Unconjugated
- Epitope
- DNMT1
- Isotype
- IgG
- Antibody clone number
- EPR3521(2)
- Vial size
- 100 µl
- Concentration
- NULL
Submitted references Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura.
Milillo A, Molinario C, Costanzi S, Vischini G, La Carpia F, La Greca F, Rigante D, Gambaro G, Gurrieri F, Sangiorgi E
Journal of nephrology 2018 Oct;31(5):731-741
Journal of nephrology 2018 Oct;31(5):731-741
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Supportive validation
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Western blot - Anti-Dnmt1 antibody [EPR3521(2)]; All lanes : Anti-Dnmt1 antibody [EPR3521(2)] at 1/1000 dilution.Lane 1 : Jurkat cell lysates.Lane 2 : 293T cell lysates.Lane 3 : HeLa cell lysates.Lane 4 : HuT-78 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 183 kDa.
- Validation comment
- WB
Supportive validation
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dnmt1 antibody [EPR3521(2)]; Immunohistochemical analysis of paraffin embedded Human stomach tissue labelled with TA307586 at 1/250 dilution.
- Validation comment
- IHC
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dnmt1 antibody [EPR3521(2)]; Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with TA307586 at 1/250 dilution.
- Validation comment
- IHC
