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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- MAB0079 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB0079, RRID:AB_1017125
- Product name
- DNMT1 monoclonal antibody, clone 60B1220.1
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of DNMT1.
- Antigen sequence
EKDDREDKENAFKR- Isotype
- IgG
- Antibody clone number
- 60B1220.1
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice.
Downregulation of Toll-Like Receptor 9 Expression by Beta Human Papillomavirus 38 and Implications for Cell Cycle Control.
Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.
Epstein-Barr virus down-regulates tumor suppressor DOK1 expression.
Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters.
Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer.
Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation.
Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells.
Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin.
CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.
Du HP, Li J, You SJ, Wang YL, Wang F, Cao YJ, Hu LF, Liu CF
Biochemical and biophysical research communications 2016 Jan 15;469(3):776-82
Biochemical and biophysical research communications 2016 Jan 15;469(3):776-82
Downregulation of Toll-Like Receptor 9 Expression by Beta Human Papillomavirus 38 and Implications for Cell Cycle Control.
Pacini L, Savini C, Ghittoni R, Saidj D, Lamartine J, Hasan UA, Accardi R, Tommasino M
Journal of virology 2015 Nov;89(22):11396-405
Journal of virology 2015 Nov;89(22):11396-405
Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.
Li JJ, Li Q, Du HP, Wang YL, You SJ, Wang F, Xu XS, Cheng J, Cao YJ, Liu CF, Hu LF
International journal of molecular sciences 2015 Jun 3;16(6):12560-77
International journal of molecular sciences 2015 Jun 3;16(6):12560-77
Epstein-Barr virus down-regulates tumor suppressor DOK1 expression.
Siouda M, Frecha C, Accardi R, Yue J, Cuenin C, Gruffat H, Manet E, Herceg Z, Sylla BS, Tommasino M
PLoS pathogens 2014 May;10(5):e1004125
PLoS pathogens 2014 May;10(5):e1004125
Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters.
Saidj D, Cros MP, Hernandez-Vargas H, Guarino F, Sylla BS, Tommasino M, Accardi R
Journal of virology 2013 Nov;87(22):12139-50
Journal of virology 2013 Nov;87(22):12139-50
Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer.
Du J, Zhou N, Liu H, Jiang F, Wang Y, Hu C, Qi H, Zhong C, Wang X, Li Z
PloS one 2012;7(4):e35957
PloS one 2012;7(4):e35957
Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
Cheng JC, Auersperg N, Leung PC
Oncogene 2011 Sep 15;30(37):3930-42
Oncogene 2011 Sep 15;30(37):3930-42
Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation.
Xia G, Schneider-Stock R, Diestel A, Habold C, Krueger S, Roessner A, Naumann M, Lendeckel U
Biochemical and biophysical research communications 2008 May 2;369(2):526-31
Biochemical and biophysical research communications 2008 May 2;369(2):526-31
Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells.
Ji W, Yang L, Yu L, Yuan J, Hu D, Zhang W, Yang J, Pang Y, Li W, Lu J, Fu J, Chen J, Lin Z, Chen W, Zhuang Z
Carcinogenesis 2008 Jun;29(6):1267-75
Carcinogenesis 2008 Jun;29(6):1267-75
Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin.
Mabaera R, Greene MR, Richardson CA, Conine SJ, Kozul CD, Lowrey CH
Blood 2008 Jan 1;111(1):411-20
Blood 2008 Jan 1;111(1):411-20
CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.
Guastafierro T, Cecchinelli B, Zampieri M, Reale A, Riggio G, Sthandier O, Zupi G, Calabrese L, Caiafa P
The Journal of biological chemistry 2008 Aug 8;283(32):21873-80
The Journal of biological chemistry 2008 Aug 8;283(32):21873-80
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.
Villa R, Pasini D, Gutierrez A, Morey L, Occhionorelli M, Viré E, Nomdedeu JF, Jenuwein T, Pelicci PG, Minucci S, Fuks F, Helin K, Di Croce L
Cancer cell 2007 Jun;11(6):513-25
Cancer cell 2007 Jun;11(6):513-25
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis for DNMT1. Using DNMT1 monoclonal antibody, clone 60B1220.1 (Cat # MAB0079) at 2 ug/mL against 10 ug of cell lysates of mouse ES cell.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- IHC analysis of DNMT1. Using DNMT1 monoclonal antibody, clone 60B1220.1 (Cat # MAB0079) at 2 ug/mL on formalin-fixed, paraffin-embedded medullar kidney tissue sections.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
