BS6604

antibody from Bioworld Technology, Inc
Targeting: FANCD2 FA-D2, FACD, FAD, FANCD
Provider product page for BS6604
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6604 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FANCD2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human FANCD2.
Description
Several FA proteins, including FANCA, FANCC, FANCF, and FANCG, interact in a nuclear complex, and this complex is required for the activation (monoubiquitination) of the downstream FANCD2 protein. When monoubiquitinated, the FANCD2 protein co-localizes with the breast cancer susceptibility protein BRCA1 in DNA damage induced foci. In male meiosis, FANCD2 also co-localizes with BRCA1 at synaptonemal complexes. The human FANCD2 gene maps to chromosome 3p25.3, contains 44 exons and encodes a 1,451-amino acid nuclear protein that exists as 2 protein isoforms.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FANCD2 protein structure - BS6604 shown in red.