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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
- Immunohistochemistry [1]
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- Product number
- PAB12428 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12428, RRID:AB_10550783
- Product name
- FANCD2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against partial recombinant FANCD2.
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Young patients with oral squamous cell carcinoma: study of the involvement of GSTP1 and deregulation of the Fanconi anemia genes.
Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia.
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.
Nbs1 is required for ATR-dependent phosphorylation events.
Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway.
Tremblay S, Pintor Dos Reis P, Bradley G, Galloni NN, Perez-Ordonez B, Freeman J, Brown D, Gilbert R, Gullane P, Irish J, Kamel-Reid S
Archives of otolaryngology--head & neck surgery 2006 Sep;132(9):958-66
Archives of otolaryngology--head & neck surgery 2006 Sep;132(9):958-66
Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia.
Mukhopadhyay SS, Leung KS, Hicks MJ, Hastings PJ, Youssoufian H, Plon SE
The Journal of cell biology 2006 Oct 23;175(2):225-35
The Journal of cell biology 2006 Oct 23;175(2):225-35
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.
Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, Bartek J, Lukas J
The Journal of cell biology 2006 Apr 24;173(2):195-206
The Journal of cell biology 2006 Apr 24;173(2):195-206
Nbs1 is required for ATR-dependent phosphorylation events.
Stiff T, Reis C, Alderton GK, Woodbine L, O'Driscoll M, Jeggo PA
The EMBO journal 2005 Jan 12;24(1):199-208
The EMBO journal 2005 Jan 12;24(1):199-208
Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway.
Rothfuss A, Grompe M
Molecular and cellular biology 2004 Jan;24(1):123-34
Molecular and cellular biology 2004 Jan;24(1):123-34
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of FANCD2 in HeLa whole cell extract using FANCD2 polyclonal antibody (Cat # PAB12428).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- FANCD2 polyclonal antibody (Cat # PAB12428) was used to stain FANCD2. FANCD2 colocalizes in vivo with another protein in U-2 OS cells after cell exposure to IR. Proliferating U-2 OS cells were exposed to 10 Gy of IR and double -color immunofluorescence staining was performed after 8 h.
- Validation comment
- Immunofluorescence
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- FANCD2 colocalizes in vivo with another protein in SiHa cells after cell exposure to IR. Proliferating SiHa cells were exposed to 10 Gy of IR and double -color immunofluorescence staining was performed after 8 h. FANCD2 were stained with FANCD2 polyclonal antibody (Cat # PAB12428).
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Staining of human prostate, glandular epithelium using FANCD2 polyclonal antibody (Cat # PAB12428).
- Validation comment
- Immunohistochemistry
