BS8424

antibody from Bioworld Technology, Inc

Targeting: TDRKH TDRD2

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8424

Provider

Bioworld Technology, Inc

Product name

TDRKH polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human TDRKH.

Description

TDRKH (tudor and KH domain-containing protein), also known as TDRD2 (tudor domain-containing protein 2), is a 561 amino acid protein that contains two KH domains and one tudor domain. TDRKH exists as two alternatively spliced isoforms and interacts with HIWI and HILI2. The gene that encodes TDRKH contains roughly 21,310 bases and maps to human chromosome 1q21. With roughly 3,000 genes that span about 260 million base pairs, chromosome 1 makes up approximately 8% of the human genome. There are also a large number of diseases associated with chromosome 1, notably, the rare aging disease Hutchinson-Gilford progeria which is associated with the LMNA gene that encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.