Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11054-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11054-1-AP, RRID:AB_2266280
- Product name
- GANP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GANP antibody (Cat. #11054-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.
GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.
GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity.
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.
Yang C, Zheng J, Xue Y, Yu H, Liu X, Ma J, Liu L, Wang P, Li Z, Cai H, Liu Y
Frontiers in molecular neuroscience 2017;10:437
Frontiers in molecular neuroscience 2017;10:437
GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.
Singh SK, Maeda K, Eid MM, Almofty SA, Ono M, Pham P, Goodman MF, Sakaguchi N
Nature communications 2013;4:1830
Nature communications 2013;4:1830
GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity.
Maeda K, Almofty SA, Singh SK, Eid MMA, Shimoda M, Ikeda T, Koito A, Pham P, Goodman MF, Sakaguchi N
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 15;191(12):6030-6039
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 15;191(12):6030-6039
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.
Maeda K, Singh SK, Eda K, Kitabatake M, Pham P, Goodman MF, Sakaguchi N
The Journal of biological chemistry 2010 Jul 30;285(31):23945-53
The Journal of biological chemistry 2010 Jul 30;285(31):23945-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11054-1-AP(GANP antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MCM3AP antibody 11054-1-AP at 1:100 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11054-1-AP(GANP antibody) at dilution of 1:10 (under 10x lens)
- Sample type
- tissue