Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 12406-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12406-1-AP, RRID:AB_10642942
- Product name
- Aconitase 1 antibody
- Antibody type
- Polyclonal
- Description
- Aconitase 1 antibody (Cat. #12406-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NMDA receptor activation induces damage of alveolar type II cells and lung fibrogenesis through ferroptosis.
SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux.
KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2.
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
Asparagine starvation suppresses histone demethylation through iron depletion.
Mitophagy, Ferritinophagy and Ferroptosis in Retinal Pigment Epithelial Cells Under High Glucose Conditions: Implications for Diabetic Retinopathy and Age-Related Retinal Diseases.
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis.
Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite.
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.
Cheng HP, Feng DD, Li XH, Gao LH, Qiu YJ, Liang XY, Zhou Y, Huang P, Shao M, Zhang YN, Chang YF, Fu JF, Huang YH, Liu W, Tang SY, Li C, Luo ZQ
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119535
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119535
SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux.
Mozzi A, Oldani M, Forcella ME, Vantaggiato C, Cappelletti G, Pontremoli C, Valenti F, Forni D, Saresella M, Biasin M, Sironi M, Fusi P, Cagliani R
iScience 2023 Jul 21;26(7):107118
iScience 2023 Jul 21;26(7):107118
KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2.
Zhou H, Chen J, Fan M, Cai H, Dong Y, Qiu Y, Zhuang Q, Lei Z, Li M, Ding X, Yan P, Lin A, Zheng S, Yan Q
Journal of experimental & clinical cancer research : CR 2023 Jan 5;42(1):5
Journal of experimental & clinical cancer research : CR 2023 Jan 5;42(1):5
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
Li MX, Wu XT, Jing WQ, Hou WK, Hu S, Yan W
Cell death & disease 2023 Aug 2;14(8):492
Cell death & disease 2023 Aug 2;14(8):492
Asparagine starvation suppresses histone demethylation through iron depletion.
Jiang J, Srivastava S, Liu S, Seim G, Claude R, Zhong M, Cao S, Davé U, Kapur R, Mosley AL, Zhang C, Wan J, Fan J, Zhang J
iScience 2023 Apr 21;26(4):106425
iScience 2023 Apr 21;26(4):106425
Mitophagy, Ferritinophagy and Ferroptosis in Retinal Pigment Epithelial Cells Under High Glucose Conditions: Implications for Diabetic Retinopathy and Age-Related Retinal Diseases.
Singh LP, Yumnamcha T, Devi TS
JOJ ophthalmology 2021;8(5):77-85
JOJ ophthalmology 2021;8(5):77-85
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis.
Cheng H, Feng D, Li X, Gao L, Tang S, Liu W, Wu X, Yue S, Li C, Luo Z
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166204
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166204
Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite.
Ceccacci S, Deitersen J, Mozzicafreddo M, Morretta E, Proksch P, Wesselborg S, Stork B, Monti MC
Biomolecules 2020 Jun 2;10(6)
Biomolecules 2020 Jun 2;10(6)
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Niu L, Ye C, Sun Y, Peng T, Yang S, Wang W, Li H
Cell & bioscience 2018;8:41
Cell & bioscience 2018;8:41
Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.
Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z, Shen G
Drug design, development and therapy 2017;11:431-439
Drug design, development and therapy 2017;11:431-439
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The Aconitase 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Aconitase 1. This antibody recognizes human,mouse,rat antigen. The Aconitase 1 antibody has been validated for the following applications: ELISA, WB analysis.