GTX123973

antibody from GeneTex

Targeting: ALDH1A1 ALDH1, PUMB1, RALDH1

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

GTX123973

Provider

GeneTex

Proper citation

GeneTex Cat#GTX123973, RRID:AB_11166810

Product name

ALDH1A1 antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat

Host

Rabbit

References

Submitted references

WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer.

Castagnoli L, Cancila V, Cordoba-Romero SL, Faraci S, Talarico G, Belmonte B, Iorio MV, Milani M, Volpari T, Chiodoni C, Hidalgo-Miranda A, Tagliabue E, Tripodo C, Sangaletti S, Di Nicola M, Pupa SM
Oncogene 2019 Jan 31;

---

TRAF6 regulates tumour metastasis through EMT and CSC phenotypes in head and neck squamous cell carcinoma.

Chen L, Li YC, Wu L, Yu GT, Zhang WF, Huang CF, Sun ZJ
Journal of cellular and molecular medicine 2018 Feb;22(2):1337-1349

---

Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma.

Ma L, Wang L, Shan Y, Nafees M, Ihab E, Zhang R, Wang F, Yin W
PloS one 2017;12(11):e0188665

---

NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma.

Huang CF, Chen L, Li YC, Wu L, Yu GT, Zhang WF, Sun ZJ
Journal of experimental & clinical cancer research : CR 2017 Sep 2;36(1):116

---

A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres.

Ni YL, Hsieh CH, Kim SH, Wang JP, Su CL, Yao CF, Fang K
Apoptosis : an international journal on programmed cell death 2017 Oct;22(10):1235-1245

---

Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma.

Wu TF, Li YC, Ma SR, Bing-Liu, Zhang WF, Sun ZJ
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Apr;39(4):1010428317695930

---

MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes.

Yan L, Cao R, Liu Y, Wang L, Pan B, Lv X, Jiao H, Zhuang Q, Sun X, Xiao R
Scientific reports 2016 Sep 6;6:28281

---

Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells.

Ju SY, Huang CY, Huang WC, Su Y
Cell death & disease 2015 Jul 2;6(7):e1801

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Sample (30 ?g of whole cell lysate) A: A549 7.5% SDS PAGE GTX123973 diluted at 1:10000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

ALDH1A1 antibody detects ALDH1A1 protein by western blot analysis.A. 50 ?g mouse liver lysate/extract 10% SDS-PAGEALDH1A1 antibody (GTX123973) dilution: 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

ALDH1A1 antibody detects ALDH1A1 protein by western blot analysis.A. 50 ?g rat liver lysate/extract 10% SDS-PAGEALDH1A1 antibody (GTX123973) dilution: 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Immunocytochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunofluorescence analysis of methanol-fixed A549, using ALDH1A1(GTX123973) antibody at 1:500 dilution.

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human gastric cancer, using ALDH1A1(GTX123973) antibody at 1:500 dilution.