BS60463

antibody from Bioworld Technology, Inc
Targeting: LIF CDF, DIA, HILDA
Provider product page for BS60463

Antibody data

Product number
BS60463 - Provider product page
Provider
Bioworld Technology, Inc
Product name
LIF polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human LIF.
Description
Embryonic stem (ES) cells are the focus of much research and represent great therapeutic potential as they can be propagated indefinitely in an undifferentiated state while possessing the ability to differentiate into all embryonic germ layers (endoderm, ectoderm and mesoderm) both in vivo and in vitro. LIF (leukemia inhibitory factor), also known as MLPLI (melanoma-derived LPL inhibitor), HILDA, DIA or CDF, is a 202 amino acid secreted protein and lymphoid factor that participates in the maintenance of ES cell pluripotency by suppressing spontaneous ES cell differentiation. Secreted LIF precursor is further processed into a biologically active glycoprotein. Expressed by a wide variety of cells including activated T lymphocytes, monocytes, mast cells and neuronal cells, LIF is suggested to promote survival and growth of axons in vitro and is involved in immune tolerance at the maternal-fetal interface. LIF may also participate in fat and bone metabolism and regulate epithelial conversion during kidney development.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
LIF protein structure - BS60463 shown in red.