LS-C148290

antibody from LSBio

Targeting: DIABLO DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC

Western blot (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Blocking/Neutralizing (Supportive data in Antibodypedia)

Antibody Data

Product number

LS-C148290

Provider

LSBio

Product name

DIABLO / SMAC Antibody LS-C148290

Antibody type

Polyclonal

Description

Antiserum

Reactivity

Human, Mouse, Rat

Host

Rabbit

Storage

Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Immunohistochemistry

Supportive validation

Submitted by

LSBio (provider)

Main image

Experimental details

Formalin-fixed, paraffin-embedded human colon stained for Smac/DIABLO using Polyclonal Antibody to Smac/DIABLO at 1:2000. A, normal colon. B and C, colon carcinoma. Only trace Smac/DIABLO immunoreactivity is seen in normal colonic epithelium (A), which is seen in the apical, foveolar cells. In contrast, strong immunoreactivity is observed in nuclear (B) and cytoplasmic (C) locations in the colon carcinoma specimen. Hematoxylin-Eosin counterstain.

Supportive validation

Submitted by

LSBio (provider)

Main image

Experimental details

Formalin-fixed, paraffin-embedded tissue section of human plasmacytoma (a mature B cell lymphoma) stained for Smac/DIABLO using Polyclonal Antibody to Smac/DIABLO at 1:2000. Intense nuclear staining is observed. Hematoxylin-Eos in counterstain.

Blocking/Neutralizing

Supportive validation

Submitted by

LSBio (provider)

Main image

Experimental details

Western blot of Smac/DIABLO human tissues and cell lines using Polyclonal Antibody to Smac/DIABLO at 1:2000. Legend. SMAC: full-length recombinant smac. RS1846 and Jurkat are tumor cell lines. All tissues are from normal donors except colon carcinoma (Colon Ca). SMAC expression was detected in all samples except spleen and normal colon.