PAB13089
antibody from Abnova Corporation
Targeting: DIABLO
DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB13089 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13089, RRID:AB_10550088
- Product name
- DIABLO polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of DIABLO.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.
Structural and biochemical basis of apoptotic activation by Smac/DIABLO.
Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri T, Huang Z, Alnemri ES
The Journal of biological chemistry 2000 Nov 17;275(46):36152-7
The Journal of biological chemistry 2000 Nov 17;275(46):36152-7
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.
Du C, Fang M, Li Y, Li L, Wang X
Cell 2000 Jul 7;102(1):33-42
Cell 2000 Jul 7;102(1):33-42
Structural and biochemical basis of apoptotic activation by Smac/DIABLO.
Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y
Nature 2000 Aug 24;406(6798):855-62
Nature 2000 Aug 24;406(6798):855-62
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of DIABLO in human heart tissue lysate in the absence (A) or presence (B) of blocking peptide with DIABLO polyclonal antibody (Cat # PAB13089) at 1 ug /mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of DIABLO in human ovary tissue with DIABLO polyclonal antibody (Cat # PAB13089) at 5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)