513501

antibody from BioLegend
Targeting: IL32 NK4, TAIF, TAIFb, TAIFd
Provider product page for 513501
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
513501 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#513501, RRID:AB_2124018
Product name
Purified anti-human IL-32‡‰‹Š
Antibody type
Monoclonal
Antigen
Recombinant human IL-32α
Description
Interleukin 32 (IL-32),previously known as a transcript (NK4), is produced by mitogen-activated lymphocytes, by IFNγ-activated epithelial cells or by IL-12 and IL-18-activated NK cells.Its expression is increased following activation of T-cells by mitogens or the activation of NK cells by IL-2.IL-32 activates NF-κ-B and p38 MAPK cytokine signal pathways. It has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues. IL-32 exists in at least four differentially spliced isoforms (α, β, γ and δ)with predicted molecular weight: ~26 kD.IL-32α is the shortest and most abundant of four potential splice variants of the pro-inflammatory cytokine IL-32.Potential modifications include myristoylation and N-glycosylation. Transfected IL-32 alpha was more likely to be cell-associated as compared to IL-32β, suggesting an intracellular function.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
IL32 protein structure - 513501 shown in red.