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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- sc-17779 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-17779, RRID:AB_628302
- Product name
- Anti-BIRC5
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human
- Host
- Mouse
Submitted references Association of telomere length with authentic pluripotency of ES/iPS cells.
TNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.
All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein.
EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.
Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression.
Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.
JC virus agnoprotein inhibits in vitro differentiation of oligodendrocytes and promotes apoptosis.
Nuclear survivin as a biomarker for non-small-cell lung cancer.
Huang J, Wang F, Okuka M, Liu N, Ji G, Ye X, Zuo B, Li M, Liang P, Ge WW, Tsibris JC, Keefe DL, Liu L
Cell research 2011 May;21(5):779-92
Cell research 2011 May;21(5):779-92
TNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.
Liu F, Hu X, Zimmerman M, Waller JL, Wu P, Hayes-Jordan A, Lev D, Liu K
PloS one 2011 Jan 17;6(1):e16241
PloS one 2011 Jan 17;6(1):e16241
All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein.
Hoang TC, Bui TK, Taguchi T, Watanabe T, Sato Y
Journal of experimental & clinical cancer research : CR 2010 Dec 16;29(1):165
Journal of experimental & clinical cancer research : CR 2010 Dec 16;29(1):165
EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.
Wang H, Gambosova K, Cooper ZA, Holloway MP, Kassai A, Izquierdo D, Cleveland K, Boney CM, Altura RA
BMC molecular biology 2010 Aug 31;11:66
BMC molecular biology 2010 Aug 31;11:66
Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression.
Zhao B, Song A, Haque R, Lei F, Weiler L, Xiong X, Wu Y, Croft M, Song J
Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 1;182(11):6744-52
Journal of immunology (Baltimore, Md. : 1950) 2009 Jun 1;182(11):6744-52
Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.
Song J, So T, Croft M
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7240-8
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7240-8
JC virus agnoprotein inhibits in vitro differentiation of oligodendrocytes and promotes apoptosis.
Merabova N, Kaniowska D, Kaminski R, Deshmane SL, White MK, Amini S, Darbinyan A, Khalili K
Journal of virology 2008 Feb;82(3):1558-69
Journal of virology 2008 Feb;82(3):1558-69
Nuclear survivin as a biomarker for non-small-cell lung cancer.
Lu B, Gonzalez A, Massion PP, Shyr Y, Shaktour B, Carbone DP, Hallahan DE
British journal of cancer 2004 Aug 2;91(3):537-40
British journal of cancer 2004 Aug 2;91(3):537-40
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Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Western blot analysis of antibody specificity using a routine panel composed of IgG/HSA-depleted human plasma and protein lysates from selected human tissues and cell lines.
- Validation comment
- Single band corresponding to the predicted size in kDa (+/-20%).
- Primary Ab dilution
- 1:500
- Secondary Ab dilution
- 1:7000
- Lane 1
- Marker [kDa]: 230, 110, 82, 49.3, 32.2, 25.5, 17.6
- Lane 2
- RT-4
- Lane 3
- U-251MG sp
- Lane 4
- A-431
- Lane 5
- Liver
- Lane 6
- Testis
- Theoretical target weight
- [kDa] 16
Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Immunohistochemical staining of human bone marrow shows strong nuclear positivity in a subset of bone marrow poietic cells.
- Validation comment
- Staining pattern consistent with experimental and/or bioinformatic data.
