GTX100052

Liu YH, Weng YP, Tsai HY, Chen CJ, Lee DY, Hsieh CL, Wu YC, Lin JY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 Jul 15;46:184-192

MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway.

Fu JH, Yang S, Nan CJ, Zhou CC, Lu DQ, Li S, Mu HQ
European review for medical and pharmacological sciences 2018 Jan;22(2):351-357

MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway.

Fu JH, Yang S, Nan CJ, Zhou CC, Lu DQ, Li S, Mu HQ
European review for medical and pharmacological sciences 2018 Jan;22(2):351-357

Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ.

Lee WY, Chen PC, Wu WS, Wu HC, Lan CH, Huang YH, Cheng CH, Chen KC, Lin CW
International journal of cancer 2017 Nov 1;141(9):1921-1931

Inhibition of miR-221 influences bladder cancer cell proliferation and apoptosis.

Liu H, Chang JK, Hou JQ, Zhao ZH, Zhang LD
European review for medical and pharmacological sciences 2017 Jul;21(14):3193-3199

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1.

Chang YF, Hsu YF, Chiu PT, Huang WJ, Huang SW, Ou G, Sheu JR, Hsu MJ
Oncotarget 2015 Jan 1;6(1):85-100

Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption.

Hsiao CJ, Hsiao G, Chen WL, Wang SW, Chiang CP, Liu LY, Guh JH, Lee TH, Chung CL
Journal of natural products 2014 Apr 25;77(4):758-65

Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade.

Chang HL, Chen CY, Hsu YF, Kuo WS, Ou G, Chiu PT, Huang YH, Hsu MJ
Biochimica et biophysica acta 2013 Aug;1830(8):4053-64

Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells.

Hsu YF, Sheu JR, Lin CH, Yang DS, Hsiao G, Ou G, Chiu PT, Huang YH, Kuo WH, Hsu MJ
Biochimica et biophysica acta 2012 Feb;1820(2):104-15

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Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Survivin antibody detects Survivin protein by western blot analysis. A. 30 ?g 293T whole cell lysate/extract B. 30 ?g HeLa whole cell lysate/extract 12% SDS-PAGE Survivin antibody (GTX100052) dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed U2OS, using Survivin(GTX100052) antibody (Geen) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Survivin antibody detects Survivin protein at nucleus by immunofluorescent analysis.Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: Survivin protein stained by Survivin antibody (GTX100052) diluted at 1:500.Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000.Blue: Hoechst 33342 staining.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Immunoprecipitation of Survivin protein from 293T whole cell extracts using 5 £gg of Survivin antibody (GTX100052).Western blot analysis was performed using Survivin antibody (GTX100052).EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Immunohistochemical analysis of paraffin-embedded human gastric cancer, using survivin (GTX100052) antibody at 1:100 dilution.