11-1006

antibody from ABEOMICS Inc.

Targeting: BIRC5 API4, EPR-1, survivin

Antibody data

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Validation data

Product number: 11-1006 - Provider product page
Provider: ABEOMICS Inc.
Product name: Anti-Survivin Antibody
Antibody type: Polyclonal
Description: Survivin is the smallest mammalian member of the IAP (Inhibitor-Of-Apoptosis) gene family. It regulates two essential cellular processes; inhibits apoptosis and promotes cell proliferation. Survivin also plays a main role in cancer progression because it prevents apoptosis by inhibition of caspase 3 and caspase 7, and by regulating the G2 and M phases of the cell cycle. Overexpression of survivin is associated with neoplasia and metastasis. Survivin might be used as a biomarker and a primary chemotherapeutic target for the detection and treatment of gastrointestinal tract cancer, especially esophageal, gastric, and colon cancers.
Reactivity: Human
Host: Rabbit
Antigen sequence: Full length recombinant Survivin pr otein was used as the immunogen for this antibody.
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing

BIRC5 protein structure - 11-1006 shown in red.