11-1006-25

antibody from ABEOMICS Inc.
Targeting: BIRC5 API4, EPR-1, survivin
Provider product page for 11-1006-25

Antibody data

Product number
11-1006-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Survivin Antibody
Antibody type
Polyclonal
Description
Survivin is the smallest mammalian member of the IAP (Inhibitor-Of-Apoptosis) gene family. It regulates two essential cellular processes; inhibits apoptosis and promotes cell proliferation. Survivin also plays a main role in cancer progression because it prevents apoptosis by inhibition of caspase 3 and caspase 7, and by regulating the G2 and M phases of the cell cycle. Overexpression of survivin is associated with neoplasia and metastasis. Survivin might be used as a biomarker and a primary chemotherapeutic target for the detection and treatment of gastrointestinal tract cancer, especially esophageal, gastric, and colon cancers.
Reactivity
Human
Host
Rabbit
Antigen sequence
Full length recombinant Survivin pr
otein was used as the immunogen for
this antibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
BIRC5 protein structure - 11-1006-25 shown in red.