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- References [4]
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- Product number
- 24280-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MEFV antibody
- Antibody type
- Polyclonal
- Description
- MEFV antibody (Cat. #24280-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes.
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Function and mechanism of pyrin and IL-10 in the regulation of the inflammasome in pulmonary vascular endothelial cells following hemorrhagic shock.
Hegdekar N, Sarkar C, Bustos S, Ritzel RM, Hanscom M, Ravishankar P, Philkana D, Wu J, Loane DJ, Lipinski MM
Autophagy 2023 Jul;19(7):2026-2044
Autophagy 2023 Jul;19(7):2026-2044
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
Mangan MSJ, Gorki F, Krause K, Heinz A, Pankow A, Ebert T, Jahn D, Hiller K, Hornung V, Maurer M, Schmidt FI, Gerhard R, Latz E
PLoS biology 2022 Nov;20(11):e3001351
PLoS biology 2022 Nov;20(11):e3001351
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J
Nature 2022 Jun;606(7914):576-584
Nature 2022 Jun;606(7914):576-584
Function and mechanism of pyrin and IL-10 in the regulation of the inflammasome in pulmonary vascular endothelial cells following hemorrhagic shock.
Jin X, Yao Y, Lu X, Xu P, Xia Y, Zhu S
Experimental and therapeutic medicine 2019 Sep;18(3):1768-1774
Experimental and therapeutic medicine 2019 Sep;18(3):1768-1774
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MEFV antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MEFV. This antibody recognizes human antigen. The MEFV antibody has been validated for the following applications: ELISA, WB analysis.
