DPABH-22377

antibody from Creative Diagnostics

Targeting: RRM1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DPABH-22377

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-22377, RRID:AB_2517717

Product name

Rabbit Anti-Human RRM1 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Reactivity

Human, Mouse, Rat, Simian, Xenopus

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL