BS8419

antibody from Bioworld Technology, Inc
Targeting: TAGLN2 HA1756, KIAA0120
Provider product page for BS8419
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8419 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TAGLN2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TAGLN2.
Description
Transgelin (also designated SM22Ï«), is expressed abundantly in smooth muscle cells. Transgelin-2 (also known as SM22Ï« homolog) is a homolog of transgelin and is also expressed in smooth muscle cells and by peritoneal B-1 cells. The human transgelin-2 gene (designated TAGLN2), which is located on chromosome 1q231-q25, encodes a 199 amino acid protein that contains a calponin-like repeat and a calponin-homology (CH) domain. Transgelin-2 may function very similarly to transgelin. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds actin, causing actin fibers to gel within minutes of binding. Binding of transgelin to actin occurs at a ratio of 1:6 actin monomers.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TAGLN2 protein structure - BS8419 shown in red.