314304

antibody from BioLegend
Targeting: ITGA2 CD49B
Provider product page for 314304
Immunohistochemistry
Flow cytometry

Antibody data

Product number
314304 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD49b
Antibody type
Monoclonal
Antigen
CD49b
Description
CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 or GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and alminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
ITGA2 protein structure - 314304 shown in red.