Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [6]
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- Product number
- NBP1-93590 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-93590, RRID:AB_11014932
- Product name
- Rabbit Polyclonal P-Rex1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human P-Rex1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments.
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Campbell AD, Lawn S, McGarry LC, Welch HC, Ozanne BW, Norman JC
PloS one 2013;8(1):e53982
PloS one 2013;8(1):e53982
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
Stadler C, Rexhepaj E, Singan VR, Murphy RF, Pepperkok R, Uhlén M, Simpson JC, Lundberg E
Nature methods 2013 Apr;10(4):315-23
Nature methods 2013 Apr;10(4):315-23
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Lindsay CR, Lawn S, Campbell AD, Faller WJ, Rambow F, Mort RL, Timpson P, Li A, Cammareri P, Ridgway RA, Morton JP, Doyle B, Hegarty S, Rafferty M, Murphy IG, McDermott EW, Sheahan K, Pedone K, Finn AJ, Groben PA, Thomas NE, Hao H, Carson C, Norman JC, Machesky LM, Gallagher WM, Jackson IJ, Van Kempen L, Beermann F, Der C, Larue L, Welch HC, Ozanne BW, Sansom OJ
Nature communications 2011 Nov 22;2:555
Nature communications 2011 Nov 22;2:555
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P-Rex1 Antibody [NBP1-93590] - Staining of human small intestine shows moderate cytoplasmic positivity in lymphoid cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P-Rex1 Antibody [NBP1-93590] - Staining of human lymph node shows moderate cytoplasmic positivity in leukocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P-Rex1 Antibody [NBP1-93590] - Staining of human kidney shows no cytoplasmic positivity as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P-Rex1 Antibody [NBP1-93590] - Staining of human hippocampus shows moderate cytoplasmic positivity in neuronal cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P-Rex1 Antibody [NBP1-93590] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P-Rex1 Antibody [NBP1-93590] - Staining in human cerebral cortex and kidney tissues . Corresponding PREX1 RNA-seq data are presented for the same tissues.