AF1668

antibody from R&D Systems

Targeting: PAPPA2 PAPP-A2, PAPPE, PLAC3

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

AF1668

Provider

R&D Systems

Product name

Human Pappalysin-2/PAPP-A2 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human Pappalysin-2/PAPP-A2 in direct ELISAs and Western blots. In Western blots, less than 1% cross-reactivity with recombinant human PAPP-A is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q9BXP8


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells.

Crosley EJ, Dunk CE, Beristain AG, Christians JK
Reproductive biology and endocrinology : RB&E 2014 Dec 4;12:123

---

Expression of pregnancy-associated plasma protein A2 during pregnancy in human and mouse.

Wang J, Qiu Q, Haider M, Bell M, Gruslin A, Christians JK
The Journal of endocrinology 2009 Sep;202(3):337-45

---

Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients.

Nishizawa H, Pryor-Koishi K, Suzuki M, Kato T, Kogo H, Sekiya T, Kurahashi H, Udagawa Y
Molecular human reproduction 2008 Oct;14(10):595-602