Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 55138-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55138-1-AP, RRID:AB_10804353
- Product name
- PRKG2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PRKG2 antibody (Cat. #55138-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references High-Risk HPV16 E6 Activates the cGMP/PKG Pathway Through Glycosyltransferase ST6GAL1 in Cervical Cancer Cells.
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease.
Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine.
Wang J, Liu G, Liu M, Cai Q, Yao C, Chen H, Song N, Yuan C, Tan D, Hu Y, Xiang Y, Xiang T
Frontiers in oncology 2021;11:716246
Frontiers in oncology 2021;11:716246
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Xiang T, Yuan C, Guo X, Wang H, Cai Q, Xiang Y, Luo W, Liu G
Cell death & disease 2021 Feb 4;12(2):150
Cell death & disease 2021 Feb 4;12(2):150
Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease.
Yin P, Liu Q, Pan Y, Yang W, Yang S, Wei W, Chen X, Hong Y, Bai D, Li XJ, Li S
EMBO reports 2020 Jun 4;21(6):e49783
EMBO reports 2020 Jun 4;21(6):e49783
Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine.
Ahsan MK, Tchernychev B, Kessler MM, Solinga RM, Arthur D, Linde CI, Silos-Santiago I, Hannig G, Ameen NA
Physiological reports 2017 Jun;5(11)
Physiological reports 2017 Jun;5(11)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 55138-1-AP(PRKG2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRKG2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PRKG2. This antibody recognizes human,mouse,rat antigen. The PRKG2 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 55138-1-AP(PRKG2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 55138-1-AP(PRKG2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue