FNab01873

antibody from FineTest Biotech
Targeting: COPS7A CSN7A
Provider product page for FNab01873
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
FNab01873 - Provider product page
Provider
FineTest Biotech
Product name
COPS7A antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
COP9 constitutive photomorphogenic
homolog subunit 7A(Arabidopsis)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
COPS7A protein structure - FNab01873 shown in red.