Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8740 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CARD11 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; Carma 1; CARD11; CARMA1
- Description
- The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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