Tissue expression
Cell line expression
Protein structure
UBN1
Ubinuclein 1Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]
Top validated antibodies |
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| Proteintech Group | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | Monoclonal |
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| GeneTex | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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